Dr. Chan Soon Choy
Dr. Chan Soon Choy
Junior Lecturer, Genetics/ Biochemistry/ Cell Physiology
Dr. Chan Soon Choy is a geneticist who obtained his PhD in Human Genetics from Universiti Putra Malaysia. He teaches in the Scientific Foundations of Medicine course at PUGSOM. His main research interest involves the delineation of the progression, invasion and recurrence of cancers at the genomic and epigenomic planes. He is currently working on profiling a family of genes that regulate development and normal physiological homeostasis. It has been reported that deregulation of these genes is associated with cancer invasion and recurrence. In addition, he is also working on elucidating the role of microRNAs in Newcastle Disease Virus (NDV)-mediated oncolysis in bladder cancer. Findings from the research will be used to improve the oncolytic activities of NDV in cancer cells, which will serve as an additional therapeutic modality.
Dr. Chan strongly believes in maximising the utility of computing power to accelerate scientific discovery. Hence, his works incorporates computational approaches as a component in his research methodology. He hopes that his current collaboration with researchers in Universiti Putra Malaysia and University of Malaya will promote the progress of cancer research in Malaysia. Besides research, he is actively takes part in activities that promote science to secondary school students. He has been involves with the organising of the National Science Challenge competition, Academy of Sciences Malaysia for the past 2 years.
Chan SC, Siraj SS, Tan SG and Yusoff K. 2006. Rapid and non-radioactive detection method of microsatellites in Mystus nemurus: A refined technique. Pertanika Journal of Tropical Agricultural Science 28(1): 73-77.
Chan SC, Tan SG, Siraj SS and Yusoff K. 2005. Newly Developed Microsatellite Markers of Mystus nemurus Tested for Cross-Species Amplification in Two Distantly Related Aquacultured Catfish Species. Asian-Australasian Journal of Animal Sciences 18(11): 1513-1518.
Chan SC, Tan SG, Siraj SS, Yusoff KM. 2001. Random Amplified Microsatellites (RAMS): An efficient method for detection of microsatellite in Mystus nemurus. Malaysian Journal of Biochemistry & Molecular Biology 6: 57.
Large-scale profilling of cancer/testis antigens (CTA) and the delineation of miRNA-mediated reversal of CTA-associated abberant demethylation in urothelial cell carcinoma.
In vitro characterization of the functional role of miR-137 in regulating KDM5B and bladder cancer stemness.
Global transcriptomic analysis of colorectal cancer cells persistently infected with Newcastle Disease Virus.
Detection of Persistent Newcastle disease virus Infection in Various Cancer Cell Lines.
PU research team: Asst. Prof Dr Abhi Veerakumarasivam, Dr Chan Soon Choy, Radha Kodiappan.